Director of Collaborative Medicine
Reproductive Endocrinologist and Fertility Specialist
Dr. Heather Hoff is a native South Dakotan, and she graduated Summa Cum Laude with a Bachelor of Science in biology and chemistry from the University of South Dakota. She obtained her medical degree and completed the Research Distinction Track at the University of Iowa Carver College of Medicine in Iowa City, Iowa. Her residency training in Obstetrics and Gynecology was completed at Mayo Clinic in Rochester, Minnesota, where she received numerous teaching and research awards, including Best Chief Resident Educator and the Resident Research Award. Dr. Hoff then ventured south for her Reproductive Endocrinology and Infertility fellowship at the University of North Carolina-Chapel Hill.
Dr. Hoff’s research during fellowship was focused on improving embryo implantation. Her clinical and translational research interests include embryo development, laboratory quality control, fertility preservation, and mental health disorders and infertility. Her research has led to numerous publications in Reproductive Endocrinology and Infertility, including the field’s leading journals, and she has presented her work both nationally and internationally. Dr. Hoff is board certified in Obstetrics and Gynecology. She is also a member of Houston Gynecological and Obstetrical Society, American Society for Reproductive Medicine, and the American College of Obstetrics and Gynecology.
Dr. Hoff enjoys all aspects of Reproductive Endocrinology, with special interest in infertility, same-sex couple fertility support, polycystic ovarian syndrome, and elective fertility preservation.
She is thrilled to be joining the HFI team and is completely committed to providing compassionate and individualized care to achieve successful outcomes.
Q: What inspired you to become a physician?
A: My fascination with medicine began as child on a small dairy farm in South Dakota. I was certain I wanted to be a veterinarian because loved caring for the animals on the farm, especially the young calves I helped deliver and feed. That was my plan until I had emergency surgery as a teenager. I was blown away by how my surgeon treated me so compassionately and skillfully. Once in medical school, though, it became obvious that my passion lies in helping people on their journey to become parents.
Q: What is your favorite job from the past?
A: Working as a nursing aid at a skilled nursing facility through college was a great experience. It was my first healthcare job and it gave me immense satisfaction to be able to care for the residents and help them enjoy their lives. This position solidified my drive to pursue medicine as a career.
Q: What are you most passionate about professionally?
A: I believe that every person has a right to pursue their reproductive goals, and I am passionate about making access to reproductive healthcare a reality.
Q: What do you and your family like to do for fun?
A: Cooking is one of my favorite hobbies because it allows me to be creative, spend time with the ones I love, and share a delicious meal.
Q: What are you passionate about outside of work?
A: I love to explore different cultures. Here in Houston, I am fortunate to be able to experience various traditions in food and festivals, and I also enjoy the opportunity to travel both nationally and internationally to immerse myself in other ways of life.
Q: What most excites you about your work and the contribution you can make?
A: I absolutely have my dream job! Being able to help people become parents is immensely satisfying. Besides the long awaited OB scan, my most rewarding moments at work involve educating patients about fertility and the mechanics of the reproductive and endocrine pathways. I am fortunate to work in a rapidly advancing field where new therapies are constantly evolving. Providing my patients current, evidence-based, and individualized care is my priority.
Q: What special awards or recognition are you most proud of?
A: I’m most proud of the Chief Resident Teaching Award. Teaching obstetric and gynecology providers not only allows me to build relationships with those future providers but also to help them educate and care for their future patients.
Q: If you could tell potential patients one thing about you, what would it be?
A: I am here to offer you education and guidance for your reproductive options based on your specific history and goals. My aim is to provide you with a compassionate and personalized treatment plan. I know this process can be anxiety provoking, but I am committed to helping you feel at ease and to achieving a successful outcome.
- Hoff HS, Crawford NM, and Mersereau, JE. Screening for psychological conditions in infertile women: provider perspectives. J Womens Health 2018; 27(4): 503-509.
- Spencer ES, Hoff HS, Steiner AZ, and Coward RM. Immediate ureterovaginal fistula following oocyte retrieval: a case and systematic review of the literature. Urol Ann 2017; 9(2): 125-130.
- Crawford NM, Hoff HS, and Mersereau, JE. Infertile patients who screen positive for depression are less likely to initiate infertility treatments. Hum Reprod 2017; 32(3): 582-587.
- Hoff HS and Mersereau, JE. Gynecologic oncology consult: options for fertility preservation. Ob.Gyn.News 2015; 50:2, 10.
- Morbeck DE, Paczkowski M, Fredrickson JR, Krisher RL, Hoff HS, Baumann NA, Moyer T, Matern D. Composition of protein supplements used for human embryo culture. J Assist Reprod Genet. 2014; 31(12): 1703-11.
- Wolff HS, Fredrickson JR, Walker DL, Morbeck DE. Advances in quality control: mouse embryo morphokinetics are sensitive markers of in vitro Hum Reprod 2013; 28(7): 1776-1782.
- Khan Z, Wolff HS, Fredrickson JR, Walker DL, Daftary GS, Morbeck DE. Mouse strain and quality control testing: improved sensitivity of the mouse embryo assay with embryos from outbred mice. Fertil Steril 2012; 99(3): 847-854.
- Carlisle JD, Hoff HS, and Mabee PM. Breeding bird inventory of Spirit Mound historic prairie in Clay County – an area being restored to tallgrass prairie. South Dakota Bird Notes 2004; 56:4, 84-96.
- Hoff HS and Mabee PM. Comparative Evaluation of PDA-based Birding Checklist Programs. Birding 2004; 36:6, 650-654.
Research Abstracts & Presentations
- Bressler LH, Yuan L, Fitz V, Hoff HS, Fritz MA, and Young SL. Granulocyte colony stimulating factor (GCSF) treatment augments human endometrial decidualization: mechanism of therapeutic effect. Submitted for presentation at American Society for Reproductive Medicine (ASRM) meeting in Denver, CO, October 2018.
- Boerwinkle CH, Hoff HS, and Tolcher MC. Obstetric and neonatal outcomes in fresh versus frozen transfer. Accepted for poster presentation at Society for Maternal Fetal Medicine (SMFM) meeting in Dallas, TX, January 2018.
- Young SL, Hoff HS, Matson B, Fitz V, Yuan L, Mathyk B, Lessey BA, and Caron K. Endometriosis reduces granulocyte colony stimulating factor receptor (GCSF-R) expression: A mechanism reducing GCSF-mediated stromal adrenomedullin expression. Accepted for oral presentation at American Society for Reproductive Medicine (ASRM) meeting in San Antonia, TX, October 2017.
- Tolcher MC, Chu DM, Hoff HS, and Aagaard KM. The impact of obesity on risk for spontaneous preterm birth. Accepted for poster presentation at Society for Maternal Fetal Medicine (SMFM) meeting in Las Vegas, NV, January 2017.
- Crawford NM, Young A, Boylan C, Hoff HS, and Berger D. Association between progesterone levels on day of trigger and oocyte maturity, embryo quality measures, and IVF cycle outcome. Accepted for poster presentation at American Society for Reproductive Medicine (ASRM) meeting in Salt Lake City, UT, October 2016.
- Hoff HS, Yuan L, Lessey BA, and Young SL. Complex differential expression of colony stimulating factor (CSF) ligands and receptors in the human endometrium. Accepted for oral presentation at American Society for Reproductive Medicine (ASRM) meeting in Salt Lake City, UT, October 2016.
- Hoff HS, Crawford NM, Mersereau JE. Provider perceptions of psychological conditions and infertility. Accepted for poster presentation at American Society for Reproductive Medicine (ASRM) meeting in Salt Lake City, UT, October 2016.
- Crawford NM, Young A, Boylan C, Hoff HS, Berger D. Association between progesterone levels at day of trigger and oocyte maturity, fertilization, and pregnancy outcomes after in vitro fertilization. Accepted for poster presentation at American Association of Bioanalysts (AAB) meeting in Las Vegas, NV, May 2016.
- Hoff HS, Jung-Yoon Y, Jeong JW, Yuan L, Lessey BA, and Young SL. Endometrial Indian Hedgehog (IHH) Mediator Gli1 and Functional Consequences of Altered BCL6 Expression. Accepted for oral presentation at Society for Reproductive Investigation (SRI) meeting in Montreal, Canada, March 2016.
- Hoff HS, Lessey BA, Yuan L, and Young SL. Granulocyte-Macrophage Colony-stimulating factor (GMCSF) is cycle regulated in human endometrium and dysregulated in women with endometriosis. Accepted for oral presentation at American Society for Reproductive Medicine (ASRM) meeting in Baltimore, MD, October 2015.
- Hoff HS, Crawford NM, Mersereau JE. Mental health disorders in infertile women: perceived effect on fertility, and willingness for psychiatric treatment. Accepted for poster presentation at American Society for Reproductive Medicine (ASRM) meeting in Baltimore, MD, October 2015.
- Hoff HS, Bargiacchi F, Lessey BA, Yuan L, and Young SL. Aryl Hydrocarbon Receptor Signaling Alters Endometrial Gene Expression: Implications for Endometriosis. Accepted for poster presentation at Society for Reproductive Investigation (SGI) meeting in San Francisco, CA, March 2015.
- Hoff HS, Savaris RF, Spencer TE, Burns GW, Lessey BA, and Young SL. Cell Separation and RNA Sequencing Yield Novel Insights Into Endometrial Physiology. Accepted for poster presentation at Society for Reproductive Investigation (SRI) meeting in San Francisco, CA, March 2015.
- Hoff HS, Brandon A, Mersereau JE. Fertility Preservation Decision Aid Increases Knowledge and Decreases Decision Conflict. Accepted for poster presentation at Pacific Coast Reproductive Society meeting in Palm Springs, CA, March 2015.
- Wolff HS, Fredrickson J, Baumann N, Moyer T, Matern D, Morbeck D. Complex protein supplements used for embryo culture contain high levels of amino acids and metals and delay timing of early cleavage events in mouse embryos. Accepted for Oral Presentation at the European Society for Human Reproduction and Embryology, London, England July 2013.
- Wolff HS, Fredrickson JR, Walker DL, Morbeck DE. Advances in quality control: mouse embryo morphokinetics are sensitive markers of in vitro stress. Accepted for Oral Presentation. Fertility and Sterility; 2012, 98(3), S30.
- Khan Z, Wolff HS, Walker DE, Fredrickson JR, Stewart EA, Morbeck DE. Do outbred mice represent a better model for Human embryos in quality control assays for IVF? Accepted for poster presentation at Society of Gynecologic Investigators (SGI) meeting in San Diego CA, March 2012.
- Wolff HS, Gada RP, Leonard PH, Coddington CC. Clinical implications of pregestational cervical length in patients undergoing IVF. Accepted for Oral Presentation. Fertility and Sterility; 2011, 96(3), S13.
- Gada RP, Brien AL, Leonard PH, Wolff HS, Jensen JR. Death and posthumous reproduction in the setting of fertility preservation. Fertility and Sterility; 2011, 96(3), S207.
- St. Louis EK, Wolff HS. Seizure occurrence in primary iodiopathic and symptomatic generalized epilepsy is predominantly diurnal. Accepted for Poster Presentation at the American Academy of Neurology, Seattle WA, April 2009.
- Wolff HS, Zimmerman BG, St. Louis EK. Seizure occurrence in primary iodiopathic and symptomatic generalized epilepsy is predominantly diurnal. Accepted for Poster Presentation at the American Neurological Association; Salt Lake City, UT, September 2008.
- Wolff, HS. Seizure periodicity is diurnal in primary generalized epilepsy. Accepted for Poster Presentation at Medical Student Research Symposium, Iowa City IA, September 2007.
- Hoff HS. (2004, April). Breeding Bird Inventory of Spirit Mound Historic Prairie in Clay County-An area being restored to tall grass prairie. Poster presented at: National Conference for Undergraduate Research; Indianapolis, IN.
- Hoff HS. (2003, September). Breeding Bird Inventory of Spirit Mound Historic Prairie in Clay County-An area being restored to tall grass prairie. Poster presented at: EPSCoR National Conference; Las Vegas, NV.
Manuscripts in Preparation
- Hoff HS, Mathyk BA, Yuan L, Fitz V, Phillips J, Lessey BA, and Young SL. The complex differential expression and regulation of the granulocyte colony stimulating factor ligand and receptor in the human endometrium and potential mechanisms for improving embryo implantation.
- Hoff HS, Brandon A, and Mersereau JE. Fertility preservation decision aid increases knowledge and decreases decision conflict.
- Boerwinkle CH, Hoff HS, and Tolcher MC. Obstetric and neonatal outcomes in fresh versus frozen transfer.
- Hoff HS and Berger, DS. Fertilization assessment in IVF and ICSI. Principles of IVF Laboratory Practice: Optimizing Performance & Outcomes, 1st edition. Montag and Morbeck. 2017: 181-186.
- Tolcher MC, Hoff HS, Aagaard KM (In Press). Endocrine Emergencies. In Michael A. Belfort (Ed.), Critical Care Obstetrics, 6th edition. Hoboken, NJ: Wiley-Blackwell.
- ASRM Corporate Member Council In-training Travel Grant 2015
- Pacific Coast Reproductive Society Scholarship Winner 2015
- Ann Harris Resident Research Award Mayo Clinic 2014
- Best Chief Resident Teacher Award Mayo Clinic 2014
- ASRM Corporate Member Council In-training Travel Grant 2012
- Research Distinction Track 2010
- American Neurological Association Medical Student Award 2008
- University of Iowa Foundation Scholarship 2008
- Carver College of Medicine Scholarship 2006-2010
- Presidential Alumni Scholarship 2001-2005
- Charles R. Estee Scholarship 2003-2004
- Joseph Spies Scholarship 2002-2003
- Bausch and Lomb Award 2001
- Girls State Scholarship 2001-2002
- Samsung Scholarship 2001-2001
- Wal-Mart Scholarship 2001-2002
HOW TO GET STARTED
Schedule your first visit with Houston Fertility Institute. An HFI Fertility expert will sit down with you and answer any questions you may have, go over our process and discuss the best options for your fertility treatment. It really is that simple.